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江苏省中药资源产业化过程协同创新中心主任——段金廒

时间:2014-04-04 14:55:12 点击: 作者: 来源:


段金廒,中国药科大学天然药物化学博士。现任南京中医药大学副校长、教授、博士研究生导师。中药资源产业化与方剂创新药物国家地方联合研究工程中心主任、江苏省中药资源产业化过程协同创新中心主任、江苏省方剂研究重点实验室主任、江苏省方剂高技术研究重点实验室主任、江苏省理血方剂创新药物工程中心主任。兼任中国药科大学、江苏大学、英国女王大学教授。
近年来致力于中药资源及资源化学、方剂功效物质及中药配伍禁忌研究,作为国家“973”计划项目首席科学家,先后承担国家973计划、国家科技支撑计划、国家自然科学基金及省重大基础研究项目等20余项;在国内外发表学术论文发表学术论文406 篇,其中SCI收录143 篇,包括国际著名杂志Chemical Reviews、Journal of Proteome Research、Molecular BioSystem、Plose One等,总影响因子318.7;主编或副主编专著5部;申请国家发明专利60余件,已授权专利30余件;以中药资源为原料研制开发中药新药5项,新药材原料及功能型产品生产批件3个,研究制(修)定国家、行业和企业产品和生产技术标准36项。培养硕博士研究生50余名,培养博士后6名;获得国家科技进步二等奖1项、部省级科技奖6项。主编或副主编专著4部。

主要研究方向:

1. 中药资源及资源化学研究与开发

中药资源化学是揭示自然资源中对人类健康及其相关领域具有应用价值或潜在价值的资源性化学成分性质、分布、积累与消长规律,并通过适宜技术集成以实现资源的合理生产与科学利用的综合性与应用性特色突出的基础学科。

研究方向:(1)基于药用生物的生长发育过程研究资源生物体化学成分的种类与分布、合成途径、积累动态与生理生态的关系及其调控机制;(2)基于药材生产与加工过程研究资源性成分的生物转化、化学转化及其变化规律;(3)基于资源开发与综合利用角度研究药用资源中各类物质的可利用价值及其资源化过程;(4)基于资源产业化过程研究促进资源性化学成分利用效率的有效提升。

2. 方药功效物质基础与配伍规律研究

通过四物汤类方用于妇科血瘀证原发性痛经的示范性研究,提出和构建了基于药味-药对-基本方-类方的方剂方药系统衍化与关联结构研究模式,形成了具有特色的类方研究体系。作为国家“973”计划项目首席科学家,通过基于十八反的中药配伍禁忌理论基础研究项目实施,围绕我国中药配伍禁忌的理论创新、研究技术体系和适宜模式构建,以揭示中药配伍禁忌机制,建立中药配伍禁忌预警系统,为临床安全用药提供指南。

近年来主持科研项目:


项目名称

项目来源

负责内容

起止时间

基于十八反的中药配伍禁忌理论基础研究

国家重点基础研究发展计划(973计划)

主持

2011-2015

银杏叶系列产品质量标准提升及银杏资源综合开发利用

国家十二五科技支撑计划项目

主持

2011-2014

药材采收、初加工、贮藏流通过程中共性关键技术研究

国家十一五科技支撑计划项目

主持

2006-2009

岷当归规范化生产及产业化示范研究

国家十一五科技支撑计划项目

主持

2007-2010

叶用银杏规范化生产及其产业化示范研究

国家十五科技支撑计划项目

主持

2001-2004

大枣配伍大戟类药材减毒机理研究

国家自然科学基金

主持

2007-2009

四物汤及类方治疗妇科血瘀证痛经的配伍规律与物质基础研究

江苏省高校自然科学重大基础研究项目

主持

2006-2009













主要社会任职:国务院学位委员会第六届学科评议组成员;中华人民共和国第十届药典委员会委员;中华中医药学会理事;中国自然资源学会理事;中国自然资源学会天然药物资源专业委员会主任委员;中药材GAP研究促进会(香港)副会长;国家自然科学基金委员会第十二届专家评审组成员;国家SFDA食品与药品评审专家组成员等。

学术荣誉:全国优秀科技工作者荣誉称号(2010年);江苏省优秀科技工作者荣誉称号(2009年);江苏省“333高层次人才”首批中青年科技领军人才;江苏省高校“青蓝工程”优秀科技创新团队学术带头人;江苏省“六大人才高峰”培养对象(2006年);江苏省有突出贡献的中青年专家(2004年);江苏省“中药资源化学与方剂效应物质基础研究优秀人才集体”带头人(2009);江苏省高校青蓝工程优秀科技创新团队带头人(2006年);国务院政府特殊津贴获得者;江苏省政府特殊津贴获得者等。


发表代表性论文目录

[1] 段金廒*, 吴启南, 宿树兰, 周荣汉. 中药资源化学学科的建立与发展.中草药, 2012, 43: 1665-1671

[2] 段金廒*. 中药资源化学研究技术体系的建立及其应用. 中国药科大学学报, 2012, 4: 289-292.

[3] 段金廒*, 严辉, 宿树兰, 钱大玮, 吴启南, 周荣汉. 药材适宜采收期综合评价模式的建立与实践. 中草药, 2010, 41 (11): 1755-1760.

[4] 段金廒*, 宿树兰, 吕洁丽, 严辉, 丁安伟. 药材产地加工传统经验与现代科学认识. 中国中药杂志, 2009, 3424: 3151-3157.

[5] 段金廒*, 宿树兰, 钱大玮, 唐于平, 周荣汉. 中药资源化学研究思路方法与进展. 中国天然药物, 2009, 7 (5): 333-340.

[6] 段金廒*, 肖小河, 宿树兰, 赵润怀, 严辉. 中药材商品规格形成模式的探讨——以当归为例. 中国现代中药, 2009, 11 (6): 14-17.

[7] 段金廒*, 周荣汉, 宿树兰, 丁安伟, 吴启南. 我国中药资源科学发展现状及展望. 自然资源学报, 2009, 24 (3): 378-386.

[8] 段金廒*, 宿树兰, 严辉, 钱大玮. 药材初加工环节与药材品质形成的探讨. 中药材, 2011, 24(1): 1-6.

[9] 宿树兰, 段金廒*, 欧阳臻, 郭盛, 刘利. 我国桑属(Morus L.)药用植物资源化学研究进展. 中国现代中药, 2012, 14(7): 1-6.

[10] 严辉, 段金廒*, 王瑞琪, 郭增祥, 钱大玮, 宋秉生, 何子清, 高鸿英. 岷县当归产量预报模型研究. 中药材, 2012, 4: 511-514.

[11] 段金廒*, 张伯礼, 范欣生, 张艳军, 高月, 林娜, 钟赣生. 中药配伍禁忌研究思路与技术体系框架. 世界科学技术(中医药现代化), 2012, 3: 1537-1546.

[12] 段金廒*, 宿树兰, 范欣生, 钱大玮, 唐于平, 尚尔鑫, 郭建明, 刘培. 基于药物相互作用探讨中药七情合和相反/相恶/相畏配伍禁忌作用模式与机制. 世界科学技术(中医药现代化), 2012, 3: 1547-1552.

[13] 陈艳琰, 钱大玮, 尚尔鑫, 钱叶飞, 刘培, 宿树兰, 郭建明, 唐于平, 段金廒*. 基于化学成分相互作用探讨芫花与甘草配伍禁忌的机制. 药学学报, 2012, 8: 1043-1048.

[14] 华永庆, 段金廒*, 钱大玮, 江曙, 丁爱华, 宿树兰, 郭建明. 胃肠道系统功能评价技术体系的建立及其在中药配伍禁忌研究中的应用. 世界科学技术中医药现代化, 2012, 14(3): 17-25.

[15] 钱叶飞, 尚尔鑫, 段金廒*, 钱大玮, 唐于平. 基于液质联用数据库技术的中药及天然药物化学成分快速鉴定方法的建立. 中国中药杂志, 2012, 37 (21): 3256-3263.

[16] 段金廒*, 吴勉华, 范欣生, 张艳军, 刘成海, 唐于平, 尚尔鑫, 王中越. 中医方药量-效关系科学问题的探讨. 南京中医药大学学报, 2010, 26 (1): 1-6.

[17] 宿树兰, 段金廒*, 李文林, 唐于平, 范欣生. 基于物质基础探讨中药十八反配伍致毒/增毒机制. 中国实验方剂学杂志, 2010, 16 (1): 123-129.

[18] 段金廒*, 宿树兰, 唐于平, 范欣生. 中药药对配伍组合的现代认识. 南京中医药大学学报, 2009, 25 (5): 330-333.

[19] 段金廒*, 范欣生, 宿树兰, 唐于平, 尚尔鑫, 李文林, 郭建明, 华永庆. 中药及方剂量效关系的研究进展与思考. 南京中医药大学学报, 2009, 25 (4): 241-245.

[20] 段金廒*, 陆茵, 陈建伟, 丁安伟, 孙世发, 朱荃, 范欣生. 方剂现代研究的思路与方法. 南京中医药大学学报(自然科学版), 2006, 22 (1): 1-3.

[21] Shulan Su, Jin-Ao Duan*, Peijuan Wang, Pei Liu, JianmingGuo, Erxin Shang, DaweiQian, Yuping Tang, Zongxiang Tang. A metabolomic study of biochemical changes in the plasma and urine of primary dysmenorrhea patients using UPLC-MS coupled with pattern recognition approach. Journal of Proteome Research, 2013, 12 (2): 852–865.

[22] Hongyue Ma, Min Hong, Jin-ao Duan*, Pei Liu, Xinsheng Fan, Erxin Shang, Shulan Su, JianmingGuo, DaweiQian, Yuping Tang. Altered cytokine gene expression in peripheral blood monocytes across the menstrual cycle in primary dysmenorrhea: a case-control study. PLos One, 2013, 8(2): e55200.

[23] Pei Liu, Jin-ao Duan*, Peijuan Wang, DaweiQian, JianmingGuo, Erxin Shang, Shulan Su, Yuping Tang, Zongxiang Tang. Biomarkers of primary dysmenorrhea and herbal formula intervention: an exploratory metabonomics study of blood plasma and urine. Molecular BioSystems, 2013, 9 (1): 77–87.

[24] Shulan Su, YongqingHua, Yanyan Wang, Wei Gu, Wei Zhou, Jin-ao Duan*, Haifeng Jiang,Ting Chen, Yuping Tang. Evaluation of the anti-inflammatory and analgesic properties of individual andcombined extracts from Commiphoramyrrha, and Boswelliacarterii.Journal of Ethnopharmacology, 2012, 139: 649-656.

[25] L. Yu, B.P. Jiang,D. Luo, X.C. Shen, S. Guo, J.A. Duan*, Y.P. Tang. Bioactive components in the fruits of Ziziphusjujuba Mill. against theinflammatory irritant action of Euphorbia plants. Phytomedicine, 2012, 19 (3-4): 239-244.

[26] Li Liu, Jin-ao Duan*, Yuping Tang, JianmingGuo, Nianyun Yang, Hongyue Ma, Xuqin Shi. Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation. Journal of Ethnopharmacology, 2012, 139 (1): 381-387.

[27] Hanqing Wang, Sheng Guo, DaweiQian, YefeiQian, Jin-ao Duan*. Comparative analysis of quinolizidine alkaloids from different parts of Sophoraalopecuroides seeds by UPLC-MS/MS. Journal of Pharmaceutical and Biomedical Analysis, 2012, 67-68: 16-21.

[28] Wei-Wei Tao, Jin-Ao Duan*, Nian-Yun Yang, Sheng Guo, Zhen-Hua Zhu, Yu-Ping Tang and Da-Wei Qian. Determination of Nucleosides and Nucleobases in the Pollen of TyphaAngustifolia by UPLC-PDA-MS. Phytochemical Analysis, 2012, 23 (4): 373-378.

[29] Rui Liu, Jin-ao Duan*, Sheng Guo, Jian-mingGuo, Da-weiQian, Yu-ping Tang. Development of a fingerprint method for animal horn classification by liquid chromatography coupled with hierarchical clustering analysis. Journal of Liquid Chromatography & Related Technologies, 2012, 35 (2):205-214.

[30] Li Liu, Hongyue Ma, Yuping Tang, Wenxing Chen, Yin Lu, JianmingGuo, Jin-ao Duan*. Discovery of estrogen receptor a modulators from natural compounds in Si-Wu-Tang series decoctions using estrogen-responsive MCF-7 breast cancer cells. Bioorganic & Medicinal Chemistry Letters, 2012, 22 (1): 154-163.

[31] Pei Liu, Jin-ao Duan*, Jian-ming Guo, Er-Xin Shang, Da-wei Qian,Shu-lan Su and Yu-ping Tang. Identification of major chemical constituents and their metabolites in rat plasma and various organs after oral administration of effective Xiang-Fu-Si-Wu Decoction fraction by UPLC-Q-TOF-MS and MetabolynxTM. Journal of Liquid Chromatography & Related Technologies, 2013, DOI:10.1080/10826076.2012.698676.

[32] Wei-Wei Tao, Jin-Ao Duan*, Nian-Yun Yang, Yu-Ping Tang, Meng-Zhu Liu, Ye-FeiQian. Antithrombotic phenolic compounds from Glycyrrhiza uralensis. Fitoterapia, 2012, 83(2):422-425.

[33] G. Yu, Y.X. Ma, J.-A. Duan*, B.S. Song, Z.Q. He. Identification of differentially expressed genes involved in early bolting of Angelica sinensis (Apiaceae). Genetics and Molecular Research, 2012, 11 (1): 494-502.

[34] Sheng Guo, Jin-ao Duan*, Yuping Tang, DaweiQian, Zhenhua Zhu, YefeiQian, ErxinShang, Shulan Su. UHPLC-TOFMS coupled with chemometric method as a powerful technique for rapid exploring of differentiating components between two Ziziphus species. Journal of Separation Science, 2011, 34(6): 659-666.

[35] Shulan Su, Tuanjie Wang, Jin-Ao Duan*, Wei Zhou, Yong-Qing Hua, Yu-Ping Tang, Li Yu, Da-Wei Qian. Anti-inflammatory and analgesic activity of different extracts of Commiphoramyrrha. Journal of Ethnopharmacology, 2011, 134 (2): 251-258.

[36] Sheng Guo, Jin-ao Duan*, Yu Ping Tang, ShuLan Su, Da Wei Qian. Triterpenoid acids from Ziziphus jujube. Chemistry of Natural Compounds, 2011, 47 (1): 138-139.

[37] Rui Liu, Jin-ao Duan*, Min Wang, Erxin Shang, Jianming Guo, Yuping Tang. Analysis of active components of rhinoceros, water buffalo and yak horns using two-dimensional electrophoresis and ethnopharmacological evaluation. Journal of Separation Science, 2011, 34 (3): 354-362.

[38] Pei Liu, Jin-ao Duan*, Yong qingHua, Yu ping Tang, Xin Yao, Shulan Su. Effects of Xiang-Fu-Si-Wu Decoction and its main components for dysmenorrhea on uterus contraction. Journal of Ethnopharmacology, 2011, 133 (2): 591-597.

[39] JianmingGuo, Erxin Shang, Jin-ao Duan*, Yuping Tang, DaweiQian. Determination of ligustilide in the brains of freely moving rats using microdialysis coupled with ultra performance liquid chromatography/mass spectrometry. Fitoterapia, 2011, 82 (3): 441-445.

[40] JianmingGuo, CaifuXue, Jin-ao Duan*, Er-xin Shang, DaweiQian, Yuping Tang, QiangOuyang, Mei Sha. Fast characterization of constituents in HuangKui capsules using UPLC-QTOF-MS with collision energy and MassFragment software. Chromatographia, 2011, 73 (5-6): 447-456.

[41] Caifu Xue, Jianming Guo, Dawei Qian*, Jin-ao Duan*, Erxin Shang, Yan Shu, Yuwei Lu. Identification of the potential active components of Abelmoschusmanihot in rat blood and kidney tissue by microdialysis combined with ultra-performance liquid chromatography/ quadrupole time-of-flight mass spectrometry. Journal of Chromatography B, 2011, 879 (5-6): 317-325.

[42] Shulan Su, Jianming Guo, Jin-ao Duan*, Tuanjie Wang, Erxin Shang, Dawei Qian, Yuping Tang, Anwei Ding. Ultra-performance liquid chromatography-tandem mass spectrometry analysis of the bioactive components and their metabolites of ShaofuZhuyu decoction active extract in rat plasma. Journal of Chromatography B, 2010, 878 (3-4): 355–362.

[43] Min Zhu, Yuping Tang, Jin-ao Duan*, Jianming Guo, Sheng Guo, Shulan Su, Erxin Shang, Dawei Qian, Anwei Ding. Roles of paeoniflorin and senkyunolide I in SiWu decoction on antiplatelet and anticoagulation activities. Journal of Separation Science, 2010, 33 (21), 3335–3340.

[44] Li Liu, Hongyue Ma, Nianyun Yang, Yuping Tang, Jianming Guo, Weiwei Tao, Jin-ao Duan*. A series of natural flavonoids as thrombin inhibitors: structure-activity relationships. Thrombosis Research, 2010, 126 (5): 365–378.

[45] Li Liu, Jin-Ao Duan*, Yu Ping Tang, Hong Yue Ma, ShuLan Su, Jian Ming Guo, Yong Qing Hua. The protective effects of the active fraction of ShaofuZhuyu decoction on hydrogen peroxide-induced oxidative injury in vascular smooth muscle cells. Molecules, 2010, 15 (8): 5066–5078.

[46] Yuping Tang, Min Zhu, Sheng Yu, Yongqing Hua, Jin-Ao Duan*, Shulan Su, Xu Zhang, Yin Lu, Anwei Ding. Identification and comparative quantification of bio-active phthalides in essential oils from Si-Wu-Tang, Fo-Shou-San, Radix Angelica and RhizomaChuanxiong. Molecules, 2010, 15(1): 341–351.

[47] Shulan Su, Yongqing Hua, Jin-Ao Duan*, Wei Zhou, Erxin Shang, Yuping Tang. Inhibitory Effects of Active Fraction and Its Main Components of ShaofuZhuyu Decoction on Uterus Contraction. American Journal of Chinese Medicine, 2010, 38 (4): 777–787.

[48] Wei Zhou, ShuLan Su*, Jin-Ao Duan*, Jian Ming Guo, Da Wei Qian, ErXin Shang, Jin Zhang. Characterization of the active constituents in Shixiao San using bioactivity evaluation followed by UPLC-QTOF and Markerlynx analysis. Molecules, 2010, 15 (9): 6217–6230.

[49] Jin-ao Duan*, Pengfei Hou, Yuping Tang, Pei Liu, Shulan Su, Hanqing Liu. A new sesquiterpene and other constituents fromSaussurealappa root. Natural Product Communications, 2010, 5 (10): 1531-1534.

[50] Sheng Guo, Jin-Ao Duan*, Yu-Ping Tang, Zhen-Hua Zhu, Ye-FeiQian, Nian-Yun Yang, Er-Xin Shang, Da-Wei Qian. Characterization of nucleosides and nucleobases in fruits of Ziziphusjujuba by UPLC-DAD-MS. Journal of Agricultural and Food Chemistry, 2010, 58 (19), 10774–10780.

[51] Sheng Guo, Jin-Ao Duan*, Yu-Ping Tang, Nian-Yun Yang, Da-Wei Qian, Shu-Lan Su, Er-Xin Shang. Characterization of triterpenic acids in fruits of Ziziphus species by HPLC-ELSD-MS. Journal of Agricultural and Food Chemistry,2010, 58 (10), 6285–6289.

[52] Pei Liu, Li Liu, Yu Ping Tang, Jin-Ao Duan*, Nian Yun Yang. A new cerebroside and its anti-proliferation effect on VSMCs from the radix of Cyperusrotundus L. Chinese Chemical Letters, 2010, 21 (5): 606–609.

[53] Wei Wei Tao, Nian Yun Yang, Li Liu, Jin-Ao Duan*, De Kang Wu, Da Wei Qian, Yu Ping Tang. Two new cerebrosides from the pollen of Typhaangustifolia. Fitoterapia. 2010, 81 (3): 196–199.

[54] Wei Wei Tao, NianYun Yang, Jin-Ao Duan*, De Kang Wu, ErXin Shang, Da Wei Qian, Yu Ping Tang. Two new nonacosanetriols from the pollen of Typhaangustifolia. Chinese Chemical Letters, 2010, 21 (2): 209–212.

[55] Ying Chen, Jin-ao Duan*, Dawei Qian, Jianming Guo, Bingsheng Song, Ming Yang. Assessment and comparison of immunoregulatory activity of four hydrosoluble fractions of Angelica sinensis in vitro on the peritoneal macrophages in ICR mice. International Immunopharmacology, 2010, 10 (4): 422–430.

[56] Rui Liu, Min Wang, Jin-ao Duan*, Jian-ming Guo, Yu-ping Tang. Purification and identification of three novel antioxidant peptides from Cornububali (water buffalo horn). Peptides, 2010, 31 (5): 786–793.

[57] Nian-Yun Yang, Wei-Wei Tao, Min Zhu, Jin-Ao Duan*, Jian-Guo Jiang. Two new isopimaranediterpenes from the feces of Trogopterusxanthipes. Fitoterapia, 2010, 81 (5): 381-384.

[58] Nian Yun Yang, Jin-Ao Duan*, ErXin Shang, Li Juan Tian. Analysis of Sesquiterpene Lactones in Eupatorium lindleyanum by HPLC-PDA-ESI-MS/MS. Phytochemical Analysis, 2010, 21 (2): 144–149.

[59] Nian-Yun Yang, Li Liu, Wei-Wei Tao, Jin-Ao Duan*, Li-Juan Tian. Diterpenoids from Pinusmassoniana resin and their cytotoxicity against A431 and A549 cells. Phytochemistry, 2010, 71 (13): 1528–1533.

[60] Nian Yun Yang, Wei Wei Tao, Jin-Ao Duan*, Antithrombotic flavonoids from the faeces of Trogopterusxanthipes. Natural Product Research, 2010, 24 (19): 1843–1849.

[61] Jianming Guo, Jin-ao Duan*, Yuping Tang, Ning Jia, Xinghu Li, Ji Zhang. Fast onset of action and the analgesic and sedative efficacy of essential oil from RhizomaChuanxiong after nasal administration. Pharmazie, 2010, 65 (4): 296–299.

[62] Jianming Guo, Erxin Shang, Jin-ao Duan*, Yuping Tang, Dawei Qian, Shulan Su. Fast and automated characterization of major constituents in rat biofluid after oral administration of Abelmoschusmanihot extract using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry and MetaboLynx. Rapid Communications in Mass Spectrometry, 2010, 24 (4): 443–453.

[63] Yue Gu, Dawei Qian*, Jin-ao Duan*, Zhenzhong Wang, Jianming Guo, Yuping Tang, Sheng Guo. Simultaneous determination of seven main alkaloids of Chelidoniummajus L. by ultraperformance LC with photodiode-array detection. Journal of Separation Science, 2010, 33 (8), 1004–1009.

[64] Rui Liu, Min Wang, Jin-Ao Duan*. Antipyretic and antioxidant activities of the aqueous extract of Cornububali (Water Buffalo Horn). The American Journal of Chinese Medicine, 2010, 38 (2): 293–306.

[65] 朱振华, 尚尔鑫, 段金廒*, 钱大玮, 唐于平. 中药方剂化学成分液质联用分析中标准质谱库的建立和应用. 分析化学, 2010, 38 (11): 1588-1592.

[66] Jie Li Lü, Jing Zhao, Jin-Ao Duan*, Hui Yan, Yu Ping Tang, Lai Bin Zhang. Quality evaluation of Angelica sinensis by simultaneous determination of ten compounds using LC-PDA. Chromatographia, 2009, 70 (3-4): 455-465.

[67] Jie Li Lü, Jin Ao Duan*, Yu Ping Tang, Nian Yun Yang, Lai Bin Zhang. Phthalide mono- and dimers from the radix of Angelica sinensis. Biochemical Systematics and Ecology, 2009, 37 (4): 405-411.

[68] Xiangchun Shen, Yuping Tang, Ruihui Yang, Li Yu, Taihui Fang, Jin-ao Duan*. The protective effect of Zizyphus jujube fruit on carbon tetrachloride-induced hepatic injury in mice by anti-oxidative activities. Journal of Ethnopharmacology, 2009, 122 (3): 555–560.

[69] Sheng Guo, Jin-ao Duan*, Yuping Tang, Shulan Su, Erxin Shang, Shumao Ni, DaweiQian. High-performance liquid chromatography—two wavelength detection of triterpenoid acids from the fruits of Ziziphusjujuba containing various cultivars in different regions and classification using chemometric analysis. Journal of Pharmaceutical and Biomedical Analysis, 2009, 49 (5): 1296–1302

[70] Sheng Guo, Yu Ping Tang, Jin-Ao Duan*, ShuLan Su, An Wei Ding. Two new terpenoids from fruits ofZiziphus jujube. Chinese Chemical Letters, 2009, 20 (2): 197–200.

[71] ShuLan Su, Jin-Ao Duan*, Yu Ping Tang, Xu Zhang, Li Yu, FengRong Jiang, Wei Zhou, Dan Luo, An Wei Ding. Isolation and biological activities of neomyrrhaol and other terpenes from the resin of Commiphoramyrrha. PlantaMedica, 2009, 75 (4): 351–355.

[72] Nian Yun Yang, Wei Wei Tao, Jin-Ao Duan*, Jian Ming Guo, Ling Ling Cao. Four new fatty acid esters from the feces of Trogopterusxanthipes. Lipids, 2009, 44 (9): 849–853.

[73] Nian Yun Yang, Jin-Ao Duan*, Da Wei Qian. Simultaneous quantification of four sesquiterpene lactones in Eupatorium lindleyanum DC. by RP-LC. Chromatographia, 2009, 70 (1): 205–209.

[74] Nian Yun Yang, Wei Wei Tao, Jin-Ao Duan*. Three new lipids from the seeds of Trogopterusxanthipes. Journal of Chemical Research, 2009, (7): 423-426.

[75] Nianyun Yang, Weiwei Tao, Jin-ao Duan*. Determination of Biflavones from Trogopterus Feces by HPLC. Journal of Food and Drug Analysis, 2009, 17 (5): 376–379.

[76] Nianyun Yang, Weiwei Tao, Jin-ao Duan*. Four new long-chain aliphatics from the feces of Trogopterusxanthipes. Journal of Asian Natural Products Research, 2009, 11 (12): 1302– 1309.

[77] Jianming Guo, Jin-ao Duan*, Erxin Shang, Yuping Tang, Dawei Qian. Determination of ligustilide in rat brain after nasal administration of essential oil from Rhizoma Chuanxiong. Fitoterapia, 2009, 80 (3): 168–172.

[78] Jin-ao Duan*, Liuying Wang, Shihui Qian, Shulan Su, Yuping Tang. A New Cytotoxic PrenylatedDihydrobenzofuran Derivative and Other Chemical Constituents from the Rhizomes of Atractylodes lancea DC. Archieves of Pharmacal Research, 2008, 31 (8): 965-969.

[79] Shulan Su, Yongqing Hua, Jin-ao Duan*, Erxin Shang, Yuping Tang, Xingjie Bao, Yin Lu, Anwei Ding. Hypothesis of active components in volatile oil from a Chinese herbs formulation, ‘Shao-Fu-Zhu-Yu Decoction’, using GC-MS and Chemometrics. Journal of Separation Science, 2008, 31 (6): 1085-1091.

[80] Shulan Su, Li Yu, Yongqing Hua, Jin-ao Duan*, Haishan Deng, Yuping Tang, Yin Lu, Anwei Ding. Screening and analysis of potential bioactive components from ShaofuZhuyu decoction, using human umbilical vein endothelial cell extract and high performance liquid chromatography coupled with Q-TOF/MS spectrometry. Biomedical Chromatography, 2008, 22 (12): 1385-1392.

[81] Jie Li Lü, Jin-Ao Duan*, Yu Ping Tang, Two new ceramides from the radix of Angelica sinensis. Journal of Chemical Research, 2008, (11), 658-661.

[82] Yongqing Hua, Shulan Su, Jin-ao Duan*, Qiujuan Wang, Yin Lu, Long Chen. Danggui–Shaoyao–San, a traditional Chinese prescription, suppresses PGF2a production in endometrial epithelial cells by inhibiting COX-2 expression and activity. Phytomedicine, 2008, 15 (12): 1046-1052.




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